Shodex chiral HPLC columns

The Shodex ORpak CDBS-453 chiral HPLC column is designed for the high-precision separation of optical isomers. Separation is based on the conformational compatibility of the molecules, using a stationary phase containing a β-cyclodextrin derivative.

Key features:

efficient enantiomer separation
stable and reproducible peak shape
USP-NF L45 compatibility
suitable for pharmaceutical purity and impurity testing

Typical applications:

chiral active pharmaceutical ingredients (e.g. epinephrine)
enantiomeric purity testing
pharmaceutical QC and method development

Aqueous SEC (GFC) columns for bio-nanoproduct analysis and preparative use (polymer-based)

The polymer-based aqueous size-exclusion (SEC/GFC) columns in the Shodex UB series are specifically designed for the analysis of biological products and bio-nanoproducts where low backpressure and high separation efficiency are required.

Key benefits:

optimised pore structure for VLPs, exosomes and nanoparticles
low backpressure, high flow performance
excellent stability with eluents used in bioprocessing

Application areas:

exosome analysis
virus-like particles (VLPs)
protein and nano-biomolecule fractionation
preparative purification from biotechnology samples

Pretreatment columns for column switching methods

The Shodex MSpak GF-4A pretreatment column is designed to efficiently remove proteins from samples in column-switching configurations, protecting the main analytical column.

Features:

high protein-removal efficiency
removal of surfactants

Typical uses:

pretreatment of biological samples
pharmaceutical and clinical analysis
automated HPLC systems

GPC Clean-up columns – sample clean-up from complex matrices

Shodex CLNpak EV series GPC clean-up columns are designed to remove pesticide residues, fats and interfering components from food and environmental samples.

Key benefits: