Hamilton Cation-Exchange HPLC Columns

Hamilton Cation-Exchange HPLC Columns

Cation-exchange chromatography columns (Cation Exchange Columns)

Hamilton cation-exchange columns are packed entirely with polymer-based (PS-DVB) media, enabling:

• use across the full pH range
• high chemical stability
• and the use of strongly acidic or alkaline eluents without damaging the column

Polymer-Based Cation-Exchange HPLC Columns – PRP-X Series

Hamilton PRP-X series cation-exchange columns are available with various functionalised media and exchange capacities, covering applications ranging from simple inorganic ions to more complex organic and transition-metal ions.

General overview

PRP-X200

• For the rapid and selective separation of alkali and alkaline-earth metals, ammonium, and organic and inorganic cations.
• The separation can be finely controlled through the mobile-phase composition, reducing interference from other ions.

Special applications – glyphosate and its metabolites

PRP-X400

• A column specifically optimised for the analysis of glyphosate and its degradation products, particularly in drinking-water analysis.
• Its high exchange capacity enables rapid separation, even without column heating.

Transition metals and multivalent cations

PRP-X800 (WCX)

• A weak cation-exchange column suitable for separating mono- and divalent metal ions such as lithium, sodium, potassium, magnesium and calcium, as well as transition metals (manganese, zinc, cobalt and cadmium).
• It remains stable at various organic-solvent concentrations, and its exchange capacity can be dynamically controlled.

Carbohydrate and Sugar Analysis – HC-40 and HC-75 Columns

• The HC-40 and HC-75 series comprises soft-gel cation-exchange columns specifically developed for separating carbohydrates and sugar derivatives.

The cation-exchange columns are available:

• in stainless-steel and PEEK configurations,
• in analytical and preparative dimensions,
• with guard columns and cartridge systems,
• as bulk resin for method development and custom applications.

Extensive range – catalogue-based search

Cation-exchange HPLC columns are available in hundreds of possible configurations (functionalisation, exchange capacity, ionic form, column dimensions and format), so the complete range is not listed individually on this page.